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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1728182Generated: November 1, 2026

Pyrrolidine → HCID 86760822, compound

https://huagongshe.com/reaction/1728182

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant2,5-DichlorobenzaldehydeHCID 80702—
Reactant6-Chloro-1,3-dihydroindol-2-oneHCID 736344—
SolventMethanolHCID 887—
ProductHCID 86760822HCID 86760822107.8%

Reaction Steps

In a manner similar to the method described in Example 227b, 2,5-dichloro-benzaldehyde (5 g, 28.57 mmol) was reacted with 6-chlorooxindole (4.77 g, 28.57 mmol) and pyrrolidine (2.43 g, 34.3 mmol) in methanol to give title compound as yellow solid (10 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07495007B2
Source datasetuspto-grants-2009_02
ORD IDord-1ae94846b268466da8ef8466d2b827b5
Source noteuspto-grants-2009_02