HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Bromopropane → 2-[4-(5-[Propyloxy]-1-pentyl)phenyl]-5-hydroxypyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Bromopropane | HCID 7840 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | HCID 19017137 | HCID 19017137 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 2-[4-(5-[Propyloxy]-1-pentyl)phenyl]-5-hydroxypyridine | HCID 19017092 | 77,7% |
Reaktionsschritte
5.1 g of 5-trimethylsilyloxy-2-(4-[5-hydroxy-1-pentyl]phenyl)pyridine, 0.7 g of sodium hydride (60-65 wt. %), 2.5 g of 1-bromopropane and 100 ml of tetrahydrofuran were reacted analogously to Example 1(f) to give 3.6 g of 5-hydroxy-2-(4-[5-(propyloxy)-1-pentyl]phenyl)pyridine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05326497 |
| Quelldatensatz | uspto-grants-1994_07 |
| ORD ID | ord-b127a732fd8541039c9eb3adb7943cfb |
| Quellennotiz | uspto-grants-1994_07 |