反应详情

12 g of 2-[4-(3-acetoxy-1-butyl)phenyl]-5-trimethylsilyloxy-pyridine, 300 ml of 0.3M phosphate buffer solution (pH 7.0), 30 ml of chloroform and 3.0 g of lipase (genus Arthobacter) are reacted to give 4.5 g of (-)-2-[4-(3-hydroxy-1-butyl)-phenyl]-5-hydroxy-pyridine and 4.2 g of (-)-2-[4-(3-acetoxy-1-butyl)phenyl]-2-hydroxy-pyridine.