Potassium Carbonate → HCID 19017938, compound

Participants

Reaction Steps

K2CO3 (30 g) is added to a solution of 20.0 g (0.112 tool) of N-(4-hydroxyphenyl)methacrylamide in tetrahydrofuran (THF). A solution of 27 g (0.124 tool) of di-tert-butyl pyrocarbonate (di-tert-butyl dicarbonate) in THF is then added at room temperature while stirring. The reaction is complete after a few hours. The reaction mixture is poured onto ice and extracted with ethyl acetate, the organic phase is dried and the solvent is distilled off. A white crystalline product is obtained which is recrystallized from diisopropyl ether.

Provenance & Evidence