Sodium hydride → HCID 178517456, compound

Participants

Reaction Steps

A mixture of 3-Benzamidoindole-2-carboxamide (276 mg), sodium hydride (5 mg) and ethanol (5 mL) was refluxed for 2 h. The reaction mixture was quenched with saturated ammonium carbonate and the product was extracted with methylene chloride. After drying over magnesium sulfate, the solvent was removed in vacuo and the residue was triturated with ether to afford 4-Hydroxy-2-phenyl-5H-indolo[3,2-d]pyrimidine (Compound 2) as a white solid.

Provenance & Evidence