Benzoyl Peroxide → 4-(Bromomethyl)benzophenone

HRID 1728440Notes

Reaction equation

HRID 1728440 reaction equation
[C:1]([C:9]1[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:16]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[C:1]([C:9]1[CH:10]=[CH:11][C:12]([CH2:15][Br:16])=[CH:13][CH:14]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 7187Benzoyl PeroxideHCID 86524-MethylbenzophenoneHCID 67184N-bromobutanimide

Product 1

HCID 1229514-(Bromomethyl)benzophenone

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

To a solution of 4.0 g (20 mmol) of 4-benzoyltoluene and 3.6 g (20 mmol) of N-bromosuccinimide in 120 ml of carbon tetrachloride was added 0.05 g (0.2 mmol) of benzoyl peroxide. The reaction was refluxed for 17 hours, cooled to room temperature and filtered. The filtrate was evaporated and the crude product was taken on without further purification.

Workup

  1. temperatureThe reaction was refluxed for 17 hours
  2. filtrationfiltered
  3. customThe filtrate was evaporated
  4. customthe crude product was taken on without further purification

Sources & evidence

ORD record
ord-0b639e4f64e548b3b28c9099506c1821
Source dataset
uspto-grants-1994_07
Patent number
US05326905

Reaction notes

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