Methyl iodide → HCID 19014325, compound

Participants

Reaction Steps

The starting material was prepared as described in Example 3 by the alkylation with methyl iodide of 5,6-dimethyl-7-phenyl-3H,7H-pyrrolo-[2,3-d]pyrimidin-4-one (see US Patent 4,229,453). There was thus obtained 3,5,6-trimethyl-7-phenyl-3H-7H-pyrrolo-[2,3-d]pyrimidin-4-one (62.4% yield) m.p. 207°-208° C.; microanalysis, found: C, 71.0; H, 6.2; N, 16.3%; C15H15N3 requires C, 71.1; H, 5.97; N, 16.6%; NMR: CDCl3 ; 2.1(3H, s, CH3), 2.4-2.5(3H, s, CH3), 3.5-3.6(3H, s, N-CH3), 7.25-7.6(5H, complex, aromatic), 7.7-7.8(1H, s, C-H).

Provenance & Evidence