反应详情

6.83 g of 4-chloro-2-(4-methylphenyl)benzonitrile, 5.34 g of N-bromosuccinimide and 0.1 g of α,α'-azobis(isobutyronitrile) were heated in 220 ml of carbon tetrachloride under reflux for 2 hr. The succinimide was removed by filtration, and the filtrate was concentrated. The residue was crystallized from a mixed solvent of tetrahydrofuran-isopropyl ether. The yield was 5.6 g.

1. temperatureunder reflux for 2 hr
2. customThe succinimide was removed by filtration
3. concentrationthe filtrate was concentrated
4. customThe residue was crystallized from a mixed solvent of tetrahydrofuran-isopropyl ether