HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 131718539, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Benzene, 1-fluoro-4-(trifluoromethyl)- | HCID 67873 | — |
| Reactant | HCID 19014393 | HCID 19014393 | — |
| Reactant | HCID 131718540 | HCID 131718540 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 131718539 | HCID 131718539 | — |
Reaction Steps
Was prepared as described for compound (11) from the 1-(2-methylbutyl) analogue of compound (12) (2 g), NaH (0.32 g) and 4-fluorobenzotrifluoride (2.16 g) in DMF (100 ml). 3 g crude product was purified on a silica gel column identified as compound (13) by MS and 1H NMR. M.p. 237.2°-237.6° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05328917 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-6bbf6bf85764452ebf9755bfaea7968f |
| Source note | uspto-grants-1994_07 |