反应详情

A mixture of 28.5 g 3-methoxy-4-(hydroxy)benzoic acid methyl ester, 25.94 g Of finely powdered potassium carbonate, 0.070 g potassium iodide and 285 ml of 2-butanone is heated at reflux temperature for 41 hours. The reaction is cooled and filtered. The filtrate is concentrated in vacuo and recrystallized from hexane to give 40.8 g of the desired product as white crystals.

1. temperatureis heated
2. temperatureat reflux temperature for 41 hours
3. temperatureThe reaction is cooled
4. filtrationfiltered
5. concentrationThe filtrate is concentrated in vacuo
6. customrecrystallized from hexane