Iodoethane → 2-[[Acetyl[[4-(tetradecyloxy)phenyl]methyl]amino]methyl]-1-ethylpyridinium iodide

HRID 1728850Notes

Reaction equation

HRID 1728850 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][N:8]([CH2:12][C:13]1[CH:18]=[CH:17][C:16]([O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:15][CH:14]=1)[C:9](=[O:11])[CH3:10].[CH2:34]([I:36])[CH3:35]>>[I-:36].[C:9]([N:8]([CH2:7][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N+:1]=1[CH2:34][CH3:35])[CH2:12][C:13]1[CH:18]=[CH:17][C:16]([O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:15][CH:14]=1)(=[O:11])[CH3:10]

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 10004023N-(2-Pyridinylmethyl)-N-[[4-(tetradecyloxy)phenyl]methyl]acetamide

Product 1

HCID 117584032-[[Acetyl[[4-(tetradecyloxy)phenyl]methyl]amino]methyl]-1-ethylpyridinium iodide

Procedure

The title compound is prepared by the procedure of Example 28 using 0.500 g of product from Example 69 and 4.42 ml of ethyl iodide. The residue is recrystallized from methanol to give 0.554 g of the desired product as yellow crystals.

Workup

  1. customThe residue is recrystallized from methanol

Sources & evidence

ORD record
ord-9186628f177d4ae5a6071b747f8573ed
Source dataset
uspto-grants-1994_07
Patent number
US05328921

Reaction notes

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