Methyl iodide → 4-[[Acetyl[[4-(tetradecyloxy)phenyl]methyl]amino]methyl]-1-methylpyridinium iodide

HRID 1728856노트

반응식

HRID 1728856 반응식
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][N:8]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:15][CH:14]=2)[C:9](=[O:11])[CH3:10])=[CH:3][CH:2]=1.[CH3:34][I:35]>>[I-:35].[C:9]([N:8]([CH2:7][C:4]1[CH:3]=[CH:2][N+:1]([CH3:34])=[CH:6][CH:5]=1)[CH2:12][C:13]1[CH:14]=[CH:15][C:16]([O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:17][CH:18]=1)(=[O:11])[CH3:10]

참가 물질

3

반응물 2

HCID 6328Methyl iodideHCID 10095404N-(4-Pyridinylmethyl)-N-[[4-(tetradecyloxy)phenyl]methyl]acetamide

생성물 1

HCID 103484704-[[Acetyl[[4-(tetradecyloxy)phenyl]methyl]amino]methyl]-1-methylpyridinium iodide

실험 절차

The title compound is prepared by the procedure of Example 28 using 0.741 g of product from Example 77 and 5.1 ml of methyl iodide. The residue is recrystallized from methyl alcohol to give 0.933 g of the desired product as orange crystals. The spectral data indicates 2 rotomers.

후처리

  1. customThe residue is recrystallized from methyl alcohol

출처 및 근거

ORD 기록
ord-71f73592758b4503947072a627340e43
출처 데이터셋
uspto-grants-1994_07
특허 번호
US05328921

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