HRID1728867

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6340

Ethane, iodo-

C2H5I

结构：CCCCCCCCCCCCCCCCOc1ccc(OCC(=O)NCc2ccccn2)cc1

HCID19015363

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCOc1ccc(OCC(=O)NCc2cccc[n+]2CC)cc1.[I-]

HCID19014488

未命名化合物

收率 80.1%

CONDITIONS

反应条件

温度: 115 °C

PROCEDURE

实验过程

The title compound is prepared by the procedure of Example 8, using 0.50 g of product from Example 88, 8.1 g of ethyl iodide and heating the mixture at 115° C. for 22 hours. The residue is recrystallized from methyl alcohol to give 0.53 g of the desired product as light yellow prisms.

WORKUP

后处理

customThe title compound is prepared by the procedure of Example 8
customThe residue is recrystallized from methyl alcohol

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-16210f2ab9ff41b7a5502637612b88ca
来源数据集: uspto-grants-1994_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05328921
来源说明: uspto-grants-1994_07

反应 SMILES

[CH2:1]([O:17][C:18]1[CH:35]=[CH:34][C:21]([O:22][CH2:23][C:24]([NH:26][CH2:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][N:29]=2)=[O:25])=[CH:20][CH:19]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[CH2:36]([I:38])[CH3:37]>>[I-:38].[CH2:36]([N+:29]1[CH:30]=[CH:31][CH:32]=[CH:33][C:28]=1[CH2:27][NH:26][C:24](=[O:25])[CH2:23][O:22][C:21]1[CH:20]=[CH:19][C:18]([O:17][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])=[CH:35][CH:34]=1)[CH3:37]