HRID1728869

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6328

Methyl iodide

CH3I

结构：CCCCCCCCCCCCCCCCOc1ccc(OCC(=O)N(Cc2ccccn2)C(C)=O)cc1

HCID19016359

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCOc1ccc(OCC(=O)N(Cc2cccc[n+]2C)C(C)=O)cc1.[I-]

HCID19764673

未命名化合物

收率 88.1%

PROCEDURE

实验过程

The title compound is prepared by the procedure of Example 28, using 0.268 g of product from Example 90 and 3.63 g of methyl iodide. The residue is crystallized from hot methyl alcohol/chloroform to give 0.30 g of the desired product as colorless needles.

WORKUP

后处理

customThe title compound is prepared by the procedure of Example 28
customThe residue is crystallized from hot methyl alcohol/chloroform

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d0eead582af848638cd79b092b1f94d6
来源数据集: uspto-grants-1994_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05328921
来源说明: uspto-grants-1994_07

反应 SMILES

[C:1]([N:4]([CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][N:34]=1)[C:5](=[O:31])[CH2:6][O:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])=[CH:10][CH:9]=1)(=[O:3])[CH3:2].[CH3:39][I:40]>>[I-:40].[C:1]([N:4]([CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][N+:34]=1[CH3:39])[C:5](=[O:31])[CH2:6][O:7][C:8]1[CH:9]=[CH:10][C:11]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])=[CH:12][CH:13]=1)(=[O:3])[CH3:2]