1-Chloro-4-(chloromethyl)benzene → HCID 19016807, compound

Participants

Reaction Steps

The reaction and procedure are conducted in the same manner as in Example 36 using 4-chlorobenzylchloride in place of methyl iodide and using 9-bromo-5,6-dihydrothieno[2',3':2,3]thiepino[4,5-c]pyridazin-3(2H)-one in place of 9-ethyl-5,6-dihydrothieno[2',3':2,3]thiepino[4,5-c]pyridazin-3(2H)-one as used in Example 36 to give 9-bromo-2-(4-chlorobenzyl)-5,6-dihydrothieno[2',3':2,3]thiepino[4,5-c]pyridazin-3(2H)-one as white crystals, melting at 152°-154° C.

Provenance & Evidence