Sodium Hydroxide → 52086-51-8

HRID 1728974Notes

Reaction equation

HRID 1728974 reaction equation
[CH3:1][CH:2]([CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH3:14])[C:3]([O:5]C)=[O:4].[OH-].[Na+]>CO>[CH3:1][CH:2]([CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH3:14])[C:3]([OH:5])=[O:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 21804431HCID 21804431, compound

Product 1

HCID 1901687252086-51-8

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

38.45 g (200 mmol) of ester f2, 850 ml of 5% strength NaOH and 850 ml of MeOH were refluxed for 4.5 hours, the MeOH was distilled off, the product was acidified, and the ether extract was dried with MgSO4 and distilled (107°-109° C./high vacuum).

Workup

  1. distillationthe MeOH was distilled off
  2. extractionthe ether extract
  3. dry with materialwas dried with MgSO4
  4. distillationdistilled (107°-109° C./high vacuum)

Sources & evidence

ORD record
ord-7155b9fd76d04a2fa249fa932102eaf2
Source dataset
uspto-grants-1994_07
Patent number
US05329033

Reaction notes

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