Trifluoroacetic acid → HCID 19013273, compound

Participants

Reaction Steps

2.8 g (4.92 mmol) of 1,1-dimethylethyl 2-[[[2-[[3-[4-[[5-methyl-2-(1-methylethyl)phenoxy]methyl]piperidin-1-yl]propyl]amino]pyrimidin-4-yl]carbonyl]amino]ethylcarbamate in solution in 20 ml of dichloromethane are introduced into a 0.25 l round-bottomed flask, 20 ml of trifluoroacetic acid are then added and the mixture is heated at reflux for 5 h.

Provenance & Evidence