2-Chloropyrimidine-4-carboxamide → HCID 15233813, compound

Participants

Reaction Steps

2.31 g (4.92 mmol) of N-(2-aminoethyl)-2-[[3-[4-[[5-methyl-2-(1-methylethyl)phenoxy]methyl]piperidin-1-yl]propyl]amino]pyrimidine-4-carboxamide, 0.82 g (5.2 mmol) of 2-chloropyrimidine-4-carboxamide, 0.89 g (6.4 mmol) of potassium carbonateand 75 ml of acetonitrile are introduced, under an argon atmosphere, into a0.25 l round-bottomed flask and the mixture is heated at reflux for 30 h.

Provenance & Evidence