Hydrochloric Acid → HCID 15233815, compound

Participants

Reaction Steps

4.7 g. (11.16 mmol) of (±)-2-[[3-[4-(5-chloro-2-methoxyphenyl) piperazin-1-yl]-2-hydroxypropyl]amino]pyrimidine-4-carboxamide and 450 ml of methanol are introduced into a 1 l round-bottomed flask, a stream of gaseous hydrochloric acid is passed through for a few minutes and the mixture is heated at the reflux temperature of the methanol for 2 h.

Provenance & Evidence