Potassium Carbonate → HCID 15233815, compound

Participants

Reaction Steps

2.32 g (4.96 mmol) of (±)-N-(2-aminoethyl)-2-[[3-[4-(5-chloro-2-methoxyphenyl) piperazin-1-yl]-2-hydroxypropyl]amino]pyrimidine-4-carboxamide, 0.8 g (5.1mmol) of 2-chloropyrimidine-4-carboxamide and 1 g (7.2 mmol) of potassium carbonate are introduced, under an argon atmosphere, into 150 ml of acetonitrile in a 0.5 l round-bottomed flask and the mixture is heated at reflux for 17 h.

Provenance & Evidence