HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 1,8-Diazabicyclo(5.4.0)undec-7-ene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Carbonochloridate | HCID 21226386 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
Reaction Steps
Compounds of Formula (I) wherein R1 is --SO2NHCO2R22 may be prepared by reacting an appropriate chloroformate with the sulfonamide (78) in pyridine or in the presence of DBU in THF to afford the desired compound (80), as outlined in Scheme 22. ##STR40##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05330987 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-36aa48806b0b4dea87813736aef8a950 |
| Source note | uspto-grants-1994_07 |