Ethanol → HCID 54512045, compound

HRID 1729069Notes

Reaction equation

HRID 1729069 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[Cl:12])[O:5][CH2:6][CH2:7]Br.C(O)C.C(=O)([O-])[O-].[Na+].[Na+].[Cl:22][C:23]1[CH:30]=[CH:29][C:26]([CH2:27][NH2:28])=[CH:25][CH:24]=1>O>[Cl:22][C:23]1[CH:30]=[CH:29][C:26]([CH2:27][NH:28][CH2:7][CH2:6][O:5][C:4]2[CH:9]=[CH:10][C:11]([Cl:12])=[C:2]([Cl:1])[CH:3]=2)=[CH:25][CH:24]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 10340Sodium CarbonateHCID 660364-ChlorobenzylamineHCID 2807934-(2-bromoethoxy)-1,2-dichlorobenzene

Product 1

HCID 54512045HCID 54512045, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2.70 Grams (10.0 mmol) of 2-(3,4dichlorophenoxy)ethyl bromide was dissolvedin 30 ml of ethanol, followed by the addition of 1.06 g (10.0 mmol) of anhydrous sodium carbonate and 4.25 g (30.0 mmol) of 4-chlorobenzylamine. The mixture was heated and refluxed on an oil bath for 7 hours. After cooling, the reaction mixture was poured into 100 ml of water and was extracted with chloroform (20 ml×3).

Workup

  1. temperatureThe mixture was heated
  2. temperaturerefluxed on an oil bath for 7 hours
  3. temperatureAfter cooling
  4. extractionwas extracted with chloroform (20 ml×3)

Sources & evidence

ORD record
ord-f6eb65730f824eccbb8798295f631cc8
Source dataset
uspto-grants-1994_07
Patent number
US05331011

Reaction notes

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