HCID 54561140, compound → HCID 53638203, compound

HRID 1729095Notes

Reaction equation

HRID 1729095 reaction equation
C[O:2][C:3](=[O:30])[C@H:4]([CH2:19][C:20]1[CH:29]=[CH:28][C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[N:21]=1)[NH:5][C:6]([O:8][CH:9]1[CH:16]2[CH2:17][CH:12]3[CH2:13][CH:14]([CH2:18][CH:10]1[CH2:11]3)[CH2:15]2)=[O:7]>CCCCC>[CH:10]12[CH2:18][CH:14]3[CH2:13][CH:12]([CH2:17][CH:16]([CH2:15]3)[CH:9]1[O:8][C:6]([NH:5][C@H:4]([C:3]([OH:30])=[O:2])[CH2:19][C:20]1[CH:29]=[CH:28][C:27]3[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=3)[N:21]=1)=[O:7])[CH2:11]2

Participants

3

Reactant 1

HCID 54561140HCID 54561140, compound

Product 1

HCID 53638203HCID 53638203, compoundYield 52%

Reagents, catalysts & solvents 1

HCID 8003PentaneSolvent

Procedure

Method was as described for Example 30, Step 5, but using N-(2-adamantyloxy-carbonyl)-3-(quinolin-yl)-alanine methylester (1.0 g, 2 mmol) to obtain N-(2-adamantyloxy-carbonyl)-3-(quinolin-yl)-alanine (0.41 g, 42.4%) as a solid from n-pentane.

Sources & evidence

ORD record
ord-abc5b6cc110544d9a53d3170157c8bba
Source dataset
uspto-grants-1994_07
Patent number
US05331006

Reaction notes

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