Methyl iodide → HCID 53635658, compound

HRID 1729102Notes

Reaction equation

[CH3:1][C:2]([C:25]([O:27][CH3:28])=[O:26])([CH2:17][C:18]1[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][CH:19]=1)[NH:3][C:4]([O:6][CH:7]1[CH:14]2[CH2:15][CH:10]3[CH2:11][CH:12]([CH2:16][CH:8]1[CH2:9]3)[CH2:13]2)=[O:5].[C:29](=O)([O-])[O-].[K+].[K+].IC>>[CH3:29][O:24][C:21]1[CH:20]=[CH:19][C:18]([CH2:17][C:2]([CH3:1])([C:25]([O:27][CH3:28])=[O:26])[NH:3][C:4]([O:6][CH:7]2[CH:8]3[CH2:16][CH:12]4[CH2:11][CH:10]([CH2:15][CH:14]2[CH2:13]4)[CH2:9]3)=[O:5])=[CH:23][CH:22]=1

Participants

Reactant 3

HCID 6328Methyl iodide

HCID 11430Potassium Carbonate

HCID 54546551HCID 54546551, compound

Product 1

HCID 53635658HCID 53635658, compound

Procedure

The title compound was prepared from methyl α-methyl-N-[(tricyclo[3.3.1.13,7 ]dec-2-yloxy)carbonyl]-DL-tyrosinate (0.671 g, 0.0017 mmol, prepared usingthe procedure described in Example 47, Step A), potassium carbonate (0.345 g, 0.0025 mmol) and iodomethane (0.368 g, 0.0025 mol) using the procedure described in Example 47, Step B. MS: 402.4 (MH+).

Workup

customprepared usingthe procedure

Sources & evidence

ORD record: ord-ed91aaf59da7444c9518261f37f98c1b
Source dataset: uspto-grants-1994_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05331006

Reaction notes

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