Lithium hydroxide, monohydrate → HCID 54359887, compound

HRID 1729103Notes

Reaction equation

HRID 1729103 reaction equation
[CH3:1][O:2][C:3]1[CH:29]=[CH:28][C:6]([CH2:7][C:8]([CH3:27])([C:23]([O:25]C)=[O:24])[NH:9][C:10]([O:12][CH:13]2[CH:20]3[CH2:21][CH:16]4[CH2:17][CH:18]([CH2:22][CH:14]2[CH2:15]4)[CH2:19]3)=[O:11])=[CH:5][CH:4]=1.O.[OH-].[Li+]>>[CH3:1][O:2][C:3]1[CH:29]=[CH:28][C:6]([CH2:7][C:8]([CH3:27])([C:23]([OH:25])=[O:24])[NH:9][C:10]([O:12][CH:13]2[CH:20]3[CH2:21][CH:16]4[CH2:17][CH:18]([CH2:22][CH:14]2[CH2:15]4)[CH2:19]3)=[O:11])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 53635658HCID 53635658, compound

Product 1

HCID 54359887HCID 54359887, compound

Procedure

The title compound was prepared from methyl O,α-dimethyl-N-[(tricyclo[3.3.1.13,7 ]dec-2-yloxy)carbonyl]-DL-tyrosinate (0.40 g, 0.001 mmol) and lithium hydroxide monohydrate (0.066 g, 0.001 mol, 1.5 eq) using the procedure described in Example 47, Step C. MS: 388.0 (MH+); 387.0 (M+).

Sources & evidence

ORD record
ord-b4b0e9becca648fdad1350e86a3f13fa
Source dataset
uspto-grants-1994_07
Patent number
US05331006

Reaction notes

Loading…