反应详情

Benzamide (10 mmole) and 10 mmole of tetramethylammonium hydroxide in 10 g of nitrobenzene was stirred at 75°-80° C./56-63 psi (3.9 -4.4 kg/cm2) oxygen for 12 hours. Methanol/acetonitrile (4:6) (10 mL)solution was then added to homogenize the solution. A weighted aliquot was sampled for HPLC assay and revealed 20% yield of 4-nitrobenzanilide, i.e.,N-(4-nitrophenyl)benzamide. No azoxybenzene was detected.

1. aliquotA weighted aliquot was sampled for HPLC assay