HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxygen → 4-Nitrobenzanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxygen | HCID 977 | — |
| Reactant | Benzamide | HCID 2331 | — |
| Reactant | Tetramethylammonium hydroxide | HCID 60966 | — |
| Reactant | 4'-Nitrobenzanilide | HCID 76930 | — |
| Solvent | Nitrobenzene | HCID 7416 | — |
| Solvent | Acetonitrile methanol | HCID 21959252 | — |
| Product | 4-Nitrobenzanilide | HCID 77003 | 20% |
Reaction Steps
Benzamide (10 mmole) and 10 mmole of tetramethylammonium hydroxide in 10 g of nitrobenzene was stirred at 75°-80° C./56-63 psi (3.9 -4.4 kg/cm2) oxygen for 12 hours. Methanol/acetonitrile (4:6) (10 mL)solution was then added to homogenize the solution. A weighted aliquot was sampled for HPLC assay and revealed 20% yield of 4-nitrobenzanilide, i.e.,N-(4-nitrophenyl)benzamide. No azoxybenzene was detected.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05331099 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-4df96f44d270495fb04426143db9c0b9 |
| Source note | uspto-grants-1994_07 |