Water → HCID 14993983, compound

HRID 1729147Notes

Reaction equation

HRID 1729147 reaction equation
[CH:1]([Si:3]([CH3:6])([CH3:5])[CH3:4])=[CH2:2].[C:7]([O:10][C:11](Cl)=NO)(=[O:9])[CH3:8].C([N:17](CC)CC)C.[OH2:22]>CCOCC>[CH3:4][Si:3]([CH3:6])([CH3:5])[CH:1]1[O:22][N:17]=[C:8]([C:7]([O:10][CH3:11])=[O:9])[CH2:2]1

Participants

6

Reactant 4

HCID 962WaterHCID 8471TriethylamineHCID 79102VinyltrimethylsilaneHCID 131718562HCID 131718562, compound

Product 1

HCID 14993983HCID 14993983, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

3 g of vinyltrimethylsilane and 4.13 g of chloroximinomethyl acetate are introduced into 150 ml of ether, and 4.1 g of triethylamine in 150 ml of ether are then slowly added dropwise. Water is subsequently added, and the mixture is extracted several times using ether. The ether phase is dried using magnesium sulfate, concentrated on a Rotavapor and separated over a silica gel column (solvent n-heptane:ethyl acetate 9:1)

Workup

  1. additionare then slowly added dropwise
  2. extractionthe mixture is extracted several times
  3. dry with materialThe ether phase is dried
  4. concentrationconcentrated on a Rotavapor
  5. customseparated over a silica gel column (solvent n-heptane:ethyl acetate 9:1)

Sources & evidence

ORD record
ord-cbff997f54a344b8bcab8dd68fdb3e48
Source dataset
uspto-grants-1994_07
Patent number
US05332715

Reaction notes

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