反应详情

15.1 g of phenoxypropyl bromide and 60 g of piperazine were dissolved in 150 ml of dioxane, and the solution was heated at 80°-90° C. for 1 hour. The precipitated crystals were removed by filtration, and the filtrate was then concentrated. Afterward, the resultant residue was dissolved in chloroform and then washed with water. Chloroform was distilled off to obtain 15 g of 1-(3-phenoxypropyl)piperazine.

1. temperaturethe solution was heated at 80°-90° C. for 1 hour
2. customThe precipitated crystals were removed by filtration
3. concentrationthe filtrate was then concentrated
4. dissolutionAfterward, the resultant residue was dissolved in chloroform
5. washwashed with water
6. distillationChloroform was distilled off