4-Chlorophenol → HCID 131718563, compound

HRID 1729308Notes

Reaction equation

HRID 1729308 reaction equation
[Cl:1]C1C=CC(O)=CC=1.CC1C=CC(S)=CC=1.[CH3:17][N:18]1[C:23]([N:24]2[CH2:29][CH2:28][N:27]([CH2:30][CH2:31][CH2:32][S:33][C:34]3[CH:39]=[CH:38][C:37]([CH3:40])=[CH:36][CH:35]=3)[CH2:26][CH2:25]2)=[CH:22][C:21](=[O:41])[N:20]([CH3:42])[C:19]1=[O:43]>>[ClH:1].[CH3:17][N:18]1[C:23]([N:24]2[CH2:25][CH2:26][N:27]([CH2:30][CH2:31][CH2:32][S:33][C:34]3[CH:35]=[CH:36][C:37]([CH3:40])=[CH:38][CH:39]=3)[CH2:28][CH2:29]2)=[CH:22][C:21](=[O:41])[N:20]([CH3:42])[C:19]1=[O:43]

Participants

4

Reactant 3

HCID 46844-ChlorophenolHCID 78114-MethylbenzenethiolHCID 19011775HCID 19011775, compound

Product 1

HCID 131718563HCID 131718563, compound

Procedure

The same treatment as in Example 3 was effected except that 4-chlorophenol was replaced with 4-methylthiophenol, thereby obtaining 12.5 g of the crystals of 1,3-dimethyl-6-[4-(3-[4-methylthiophenoxy]propyl)piperazin-1-yl]-2,4(1H,3H)-pyrimidinedione.

Sources & evidence

ORD record
ord-d6a9ad1ad7214b0b8f77c416af03590b
Source dataset
uspto-grants-1994_07
Patent number
US05332739

Reaction notes

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