HCID 21804453, compound → HCID 21804447, compound

HRID 1729330Notes

Reaction equation

HRID 1729330 reaction equation
[CH2:1]([C:5]1[N:10]([CH2:11][C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][CH:13]=2)[C:9](=[O:21])[CH:8]=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4]>CO.[Ni]>[NH2:18][C:15]1[CH:14]=[CH:13][C:12]([CH2:11][N:10]2[C:5]([CH2:1][CH2:2][CH2:3][CH3:4])=[CH:6][CH:7]=[CH:8][C:9]2=[O:21])=[CH:17][CH:16]=1

Participants

4

Reactant 1

HCID 21804453HCID 21804453, compound

Product 1

HCID 21804447HCID 21804447, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 887MethanolSolvent

Procedure

A solution of 1.7 g of 6-butyl-1-p-nitrobenzyl-1,2-dihydro-2-oxopyridine in 50 ml of methanol is hydrogenated on 1.7 g of Raney Ni at 20° until the uptake of H2 has ceased. The mixture is filtered and evaporated to give 1-p-aminobenzyl-6-butyl-1,2-dihydro-2-oxopyridine.

Workup

  1. filtrationThe mixture is filtered
  2. customevaporated

Sources & evidence

ORD record
ord-0334e2bb363b4611b735e8e501b32f86
Source dataset
uspto-grants-1994_07
Patent number
US05332750

Reaction notes

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