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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1729333Generated: November 2, 2026

Sodium Hydroxide → HCID 19012447, compound

https://huagongshe.com/reaction/1729333

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 19012413HCID 19012413—
SolventTetrahydrofuranHCID 8028—
ProductHCID 19012447HCID 19012447—

Reaction Steps

A mixture of 404 mg of 6-butyl-1-[4-(2-methoxycarbonylanilinocarbonyl)benzyl]-1,2-dihydro-2-oxopyridine, 10 ml of 0.1N aqueous NaOH solution and 17 ml of THF is left to stand for 48 hours at 20°. The THF is evaporated off, the residue is acidified with HCl and extracted with methylene chloride and the extract is dried over Na2SO4 to give 6-butyl-1-[4-(2-carboxyanilinocarbonyl)benzyl]-1,2-dihydro-2-oxopyridine after evaporation.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05332750
Source datasetuspto-grants-1994_07
ORD IDord-3d7dca667b2f41d8a03f65682e7b9bb0
Source noteuspto-grants-1994_07