Hydrochloric Acid → HCID 19012411, compound

Participants

Reaction Steps

15 mg of NaBH4 are added at 20° to a solution of 370 mg of 6-butyl-1-(2'-cyanobiphenyl-4-ylmethyl)-3-formyl-1,2-dihydro-2-oxopyridine in 5 ml of isopropanol, with stirring. After further stirring (1 hour), dilute hydrochloric acid is added dropwise until the evolution of H2 has ceased, and the mixture is evaporated. 6-Butyl-1-(2'-cyanobiphenyl-4-ylmethyl)-3-hydroxymethyl-1,2-dihydro-2-oxopyridine is obtained after conventional working-up.

Provenance & Evidence