Hydroxyamine hydrochloride → HCID 86747994, compound

Participants

Reaction Steps

Using an analogous procedure to that described in Example 50, 5-[5-fluoro-3-(4-methoxytetrahydropyran-4-yl)phenylthio]inden-1-one was reacted with hydroxylamine hydrochloride to give 5-[5-fluoro-3-(4-methoxytetrahydropyran-4-yl)phenylthio]inden-1-one oxime in 43% yield, m.p. 124°-136° C., as a 11:9 mixture of the (E)- and (Z)-isomers;

Provenance & Evidence