反应详情

To a stirred mixture of 4-isopropoxy benzoyl chloride (15 mmol, 2.97 g) and hydroquinone (7.5 mmol, 0,825 g) in CH2Cl2 (50 ml), pyridine (2 ml) was added in 15 minutes. After stirring for 1 hour, the mixture was extracted with water, 10% HCl and water (100 ml each). Then the solvent was evaporated and the remaining solid recrystallized from ethanol/CH2Cl2 (70/30), giving 2.56 g of the product (yield 79%, melting point (mp) 195° C.).

1. additionwas added in 15 minutes
2. extractionthe mixture was extracted with water, 10% HCl and water (100 ml each)
3. customThen the solvent was evaporated
4. customthe remaining solid recrystallized from ethanol/CH2Cl2 (70/30)