Methanone, [4-(4-morpholinyl)-3-nitrophenyl]phenyl- → (3-Amino-4-morpholin-4-yl-phenyl)-phenyl-methanone

HRID 1729650Notes

Reaction equation

HRID 1729650 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:15]=[CH:16][C:17]=1[N:18]1[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8])([O-])=O>C(OCC)(=O)C>[NH2:1][C:4]1[CH:5]=[C:6]([CH:15]=[CH:16][C:17]=1[N:18]1[CH2:19][CH2:20][O:21][CH2:22][CH2:23]1)[C:7]([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:8]

Participants

3

Reactant 1

HCID 2879429Methanone, [4-(4-morpholinyl)-3-nitrophenyl]phenyl-

Product 1

HCID 1093516(3-Amino-4-morpholin-4-yl-phenyl)-phenyl-methanone

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 9.37 g. of 3-nitro-4-morpholinobenzophenone in 196 ml. of ethyl acetate is reduced as described in Examples 1 or 2. 8.26 g. of 3-amino-4-morpholinobenzophenone are obtained; m.p.: 138° C.

Sources & evidence

ORD record
ord-8b171592b5214961a051c63e4d14cd9a
Source dataset
uspto-grants-1976_11
Patent number
US03989701

Reaction notes

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