Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1729695Generated: November 3, 2026

2-Chlorobenzylideneacetone → HCID 12391100, compound

https://huagongshe.com/reaction/1729695

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorobenzylideneacetoneHCID 140760—
ReactantAmidinoacetic acid isopropyl esterHCID 12391080—
SolventIsopropanolHCID 3776—
ProductHCID 12391100HCID 1239110051%

Reaction Steps

Upon heating a solution of 18.1 g of 2-chlorobenzylideneacetone and 14.1 g of amidinoacetic acid isopropyl ester in 200 ml of isopropanol for 3 hours, 2-amino-6-methyl4-(2-chlorophenyl)-1,4-dihydropyridine-3-carboxylic acid isopropyl ester of melting point 161°C (isopropanol) is obtained. Yield: 51 percent of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03989708
Source datasetuspto-grants-1976_11
ORD IDord-696819ac1f9d4accb2523ef957f4728e
Source noteuspto-grants-1976_11