Acetyl chloride → HCID 54102714, compound

HRID 1729761Notes

Reaction equation

HRID 1729761 reaction equation
[Na].[CH2:2]([O:4][NH:5][C:6](=[C:9]1[C:14](=[O:15])[CH:13]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[C:12](C)(C)[CH2:11][C:10]1=[O:23])[CH2:7][CH3:8])[CH3:3].[C:24](Cl)(=[O:26])[CH3:25]>CC(C)=O>[C:24]([O:23][C:10]1[CH2:11][CH2:12][CH:13]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[C:14](=[O:15])[C:9]=1[C:6](=[N:5][O:4][CH2:2][CH3:3])[CH2:7][CH3:8])(=[O:26])[CH3:25]

Participants

5

Reactant 3

HCID 6367Acetyl chlorideHCID 5360545SodiumHCID 178474721HCID 178474721, compound

Product 1

HCID 54102714HCID 54102714, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Sodium salt of 2-(1-ethoxyaminopropylidene)-4-ethoxycarbonyl-5,5-dimethylcyclohexane-1,3-dione (3.1 g) was suspended in 50 ml of acetone and acetylchloride (0.8 g) was added to it at room temperature. After stirring for 3 hours, the reaction mixture was poured into ice-water and extracted with chloroform. The extract was washed with one normal sodium hydroxide and dried over magnesium sulfate. The solvent was removed is vacuo and the desired product was obtained as an oily substance.

Workup

  1. extractionextracted with chloroform
  2. washThe extract was washed with one normal sodium hydroxide
  3. dry with materialdried over magnesium sulfate
  4. customThe solvent was removed

Sources & evidence

ORD record
ord-c227be5b082a4d13a7a4f1363fa114e4
Source dataset
uspto-grants-1976_11
Patent number
US03989737

Reaction notes

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