Hydrochloric Acid → HCID 21501419, compound

Participants

Reaction Steps

2-Chloro-4-fluoro-1-naphthylamine hydrochloride-- A mixture of the above naphthalide (10 g), concd. hydrochloric acid (100 ml), and EtOH (100 ml) was refluxed for 8 hrs. The seperated material was filtered from the cold mixture, washed with water, and dried. Crystallization from EtOH gave colorless needles (16.2 g) of mp 215°-217° C.

Provenance & Evidence