HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5,6-Tetrahydrophthalic anhydride → HCID 20541555, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5,6-Tetrahydrophthalic anhydride | HCID 12475 | — |
| Reactant | 4-Chloro-2-fluoroaniline | HCID 93898 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 20541555 | HCID 20541555 | — |
Reaction Steps
4.8 Parts of 4-chloro-2-fluoroaniline were added to a solution of 5 parts of 3,4,5,6-tetrahydrophthalic anhydride in 150 parts of diethyl ether and stirred for 1.5 hours. The solution was evaporated under reduced pressure of 300 mm. Hg at 25° C to isolate 9 parts of 2-(4-chloro-2-fluorophenylaminocarbonyl)-cyclohexene-1-carboxylic acid as white crystals melting at 91°-93° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03990880 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-ddfcdd4f88f84c2b98db1307f5a0f62a |
| Source note | uspto-grants-1976_11 |