Beta-Alanine → HCID 70621101, compound

HRID 1729940Notes

Reaction equation

HRID 1729940 reaction equation
[N-:1]=[C:2]=[O:3].[NH2:4][CH:5]([C:10]([OH:12])=O)[CH2:6][CH2:7][S:8][CH3:9].N1C=CC=CC=1.N[CH2:20][CH2:21][C:22]([OH:24])=[O:23]>CO>[C:22]([CH2:21][CH2:20][N:1]1[C:10](=[O:12])[CH:5]([CH2:6][CH2:7][S:8][CH3:9])[NH:4][C:2]1=[O:3])([OH:24])=[O:23]

Participants

6

Reactant 4

HCID 239Beta-AlanineHCID 876(+-)-MethionineHCID 1049PyridineHCID 105034Isocyanate

Product 1

HCID 70621101HCID 70621101, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

189 g (1 mole) of the isocyanate derivative of the methyl ester of dl-methionine are poured slowly into a pyridine solution of β-alanine (89 g, 1 mole). The reaction takes place spontaneously, accompanied by the elimination of methanol. The reaction medium is then concentrated to dryness under reduced pressure. The residue is purified by recrystallisation from dichlorethane.

Workup

  1. concentrationThe reaction medium is then concentrated to dryness under reduced pressure
  2. customThe residue is purified by recrystallisation from dichlorethane

Sources & evidence

ORD record
ord-8af47b5592c74452afe92098d1da268d
Source dataset
uspto-grants-1976_11
Patent number
US03990883

Reaction notes

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