Hydrochloric Acid → HCID 178493816, compound

HRID 1729976Notes

Reaction equation

HRID 1729976 reaction equation
C([C:4]1[C:13]([CH2:14][O:15][C:16](=[O:18])[CH3:17])=[N+:12]([O-:19])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[O-:20])(=O)C.Cl.[CH3:22]O>>[CH3:22][O:18][C:16]1([CH3:17])[C:4]2=[N+:5]([O-:20])[C:6]3[C:11]([N+:12]([O-:19])=[C:13]2[CH2:14][O:15]1)=[CH:10][CH:9]=[CH:8][CH:7]=3

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 178475863HCID 178475863, compound

Product 1

HCID 178493816HCID 178493816, compoundYield 63%

Procedure

A suspension of 30.0 g. (0.11 mol.) of 2-acetyl-3-acetoxymethylquinoxaline 1,4-dioxide in 300 ml. of methanol, saturated with dry hydrogen chloride, was stirred at ambient temperature for 2 days. The tan solid was collected by filtration, and then it was recrystallized from methanol, to give 17.0 g. (63% yield) of 1-methoxy-1-methyl-1,3-dihydrofuro[3,4-b]quinoxaline 4,9-dioxide, m.p. 201°-202° C.

Workup

  1. additionA suspension of 30.0 g
  2. filtrationThe tan solid was collected by filtration
  3. customit was recrystallized from methanol
  4. customto give 17.0 g

Sources & evidence

ORD record
ord-e82d4852a4c646b0b79616895312111d
Source dataset
uspto-grants-1976_11
Patent number
US03991053

Reaction notes

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