Dimethylamine → HCID 21498834, compound

HRID 1730035Notes

Reaction equation

HRID 1730035 reaction equation
C([O:3][C:4]([C:6]1[O:10][N:9]=[C:8]([C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=[CH:13][CH:12]=2)[N:7]=1)=O)C.[CH3:21][NH:22][CH3:23]>>[CH3:21][N:22]([CH3:23])[C:4]([C:6]1[O:10][N:9]=[C:8]([C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=[CH:13][CH:12]=2)[N:7]=1)=[O:3]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 53762490HCID 53762490, compound

Product 1

HCID 21498834HCID 21498834, compound

Procedure

5-Ethoxycarbonyl-3-α-naphthyl-1,2,4-oxadiazole (618 mg.) was dissolved in an ethanolic solution of dimethylamine (10 ml., 33% v/v). After 1 hr. The solution was evaporated leaving a residue that was recrystallised from methanol (3.5 ml.) to give title compound (424 mg.,) m.p. 109°-110°, λmax. (EtOH) 302.5 nm (ε 9,400) νmax. (CHBr3) 1660 cm.-1 (CONMe2).

Workup

  1. customThe solution was evaporated
  2. customleaving a residue that
  3. customwas recrystallised from methanol (3.5 ml.)

Sources & evidence

ORD record
ord-04d399ce19e1461fbeb11ca2cca943a8
Source dataset
uspto-grants-1976_11
Patent number
US03991067

Reaction notes

Loading…