Gamma-Butyrolactone → 1-Benzyl-3-pyrrolidone

HRID 1730148Notes

Reaction equation

HRID 1730148 reaction equation
[C:1]1(=[O:6])O[CH2:4][CH2:3][CH2:2]1.[CH2:7]([NH2:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[CH2:7]([N:14]1[CH2:4][CH2:3][CH2:2][C:1]1=[O:6])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 7302Gamma-ButyrolactoneHCID 7504Benzylamine

Product 1

HCID 791761-Benzyl-3-pyrrolidone

Procedure

6.97 g (0.06 M) of γ-butyrolactone is mixed with 6.97 g (0.065 M) of benzylamine and heated at 190° for 24 hours. Excess benzylamine was removed at reduced pressure and the residue was distilled at 125°-130°/1 mm.

Workup

  1. temperatureheated at 190° for 24 hours
  2. customExcess benzylamine was removed at reduced pressure
  3. distillationthe residue was distilled at 125°-130°/1 mm

Sources & evidence

ORD record
ord-a40fed5f7775479baede59db222d0529
Source dataset
uspto-grants-1976_11
Patent number
US03991203

Reaction notes

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