3,4-Dichlorophenyl isocyanate → HCID 54685829, compound

Participants

Reaction Steps

To 8.1 g (0.05 mole) of 4-hydroxy-2-oxo-2H-1-benzopyran dissolved in 200 ml acetone is added 5.6 g (0.05 mole) of triethylamine, followed by the addition of 3,4-dichlorophenyl isocyanate. The mixture is heated to reflux, and in 1/2 hour none of the isocyanate is left as determined by infra-red. The acetone solution is concentrated and the yellow viscous liquid is taken up in chloroform and washed with dilute hydrochloric acid. A white solid precipitates from the chloroform-acid mixture and is collected by filtration. The insoluble white solid is slurried in boiling acetone to yield 11.0 g of pure white powder, the product, m.p. 227°C to 228°C.

Provenance & Evidence