HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → 2-(2-Formamido-5-thiadiazolyl)-1-methyl-5-nitroimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 2-(2-Amino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390816 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 2-(2-Formamido-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390860 | — |
Reaction Steps
The above compound is prepared by refluxing 8 gm. of 2-(2-amino-5-thiadiazolyl)-1-methyl-5-nitroimidazole in 30 ml. of 98% formic acid for 10 hours, cooling, and adding the mixture to saturated sodium bicarbonate solution, and the solid collected. The compound melts at 225° to 227° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03991200 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-c200d4cc94e948da8ede0395a4294332 |
| Source note | uspto-grants-1976_11 |