Dichloromethane → N-(3-{[tert-butyl(dimethyl)silyl]oxy}propyl)-2-chloro-5-fluoro-4-pyrimidinamine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[Cl:8].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:29][N:30]([c:31]1[cH:32][cH:33][cH:34][cH:35][n:36]1)[CH3:37].[Cl:38][CH2:39][Cl:40].[Cl:9][c:10]1[n:11][cH:12][c:13]([F:21])[c:14]([NH:16][CH2:17][CH2:18][CH2:19][OH:20])[n:15]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[O:20][CH2:19][CH2:18][CH2:17][NH:16][c:14]1[c:13]([F:21])[cH:12][n:11][c:10]([Cl:9])[n:15]1Participants
6
Sources & evidence
- ORD record
- ord-8063922f8db5458380bf2640280b61e6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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