反应详情

A mixture of 9.9 g. of 5-phenylvaleroylchloride and 4.6 g. of thiosemicarbazide was stirred in 20 ml. of dimethylformamide for 6 hours at 22° C. The solvent was evaporated and 10 ml. of water and 10 ml.of ether were added to the residue. The precipitate was filtered off to give the intermediate 1-(5-phenylvaleroyl)-3-thiosemicarbazide, m.p. 140°-141° C.

1. additionA mixture of 9.9 g
2. customThe solvent was evaporated
3. additionof ether were added to the residue
4. filtrationThe precipitate was filtered off