3-methylsulfanyl-1H-indole → Indole

HRID 1730299Notes

Reaction equation

HRID 1730299 reaction equation
CS[C:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[NH:5][CH:4]=1>[Ni]>[NH:5]1[C:6]2[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=2)[CH:3]=[CH:4]1

Participants

3

Reactant 1

HCID 108882523-methylsulfanyl-1H-indole

Product 1

HCID 798Indole

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

in step (d) the 3-methylthioindole from step (c) is treated with Raney nickel to form indole.

Sources & evidence

ORD record
ord-c7d49efe6c464841b077687142e3a7ef
Source dataset
uspto-grants-1976_11
Patent number
US03992392

Reaction notes

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