Ethanol → HCID 86734196, compound

HRID 1730402Notes

Reaction equation

HRID 1730402 reaction equation
[N+]([C:4]1[CH:5]=[CH:6][C:7]2[N:13]3C(CN4C(=O)C5=CC=CC=C5C4=O)=CN=[C:12]3[CH2:11][N:10]=[C:9]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[Cl:35])[C:8]=2[CH:36]=1)([O-])=O.O.[NH2:38]N.[CH2:40](O)[CH3:41]>>[Cl:35][C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=1[C:9]1[N:10]2[C:41]3[CH:40]=[CH:36][CH:4]=[CH:5][C:6]=3[CH:7]=[N:13][CH2:12][C:11]2=[N:38][CH:8]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 24654Hydrazine hydrate (1:1)HCID 21497519HCID 21497519, compound

Product 1

HCID 86734196HCID 86734196, compound

Procedure

In the manner given in Example 28, 8-nitro-1-(phthalimidomethyl)-6-(o-chlorophenyl)-4H-imidazo[1,2 -a][1,4]benzodiazepine is reacted at room temperature with hydrazine hydrate, dissolved in ethanol to give 8-nitro-1-(aminomethyl)-6 -(o-chlorophenyl-4H-imidazo[1,2-a][1,4]-benzodiazepine.

Sources & evidence

ORD record
ord-1fab3ae5790e44fa97826fa0b0321171
Source dataset
uspto-grants-1976_11
Patent number
US03992408

Reaction notes

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